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PF-232798

CAT: 0804-HY-14388Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14388Size:1 Each
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Description
PF-232798 is an orally active CCR5 antagonist with anti-HIV effects[1].
CAS Number
849753-15-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
CCR; HIV
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pf-232798.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(CN(CC2)C(C(C)C)=O)=C2N1[C@H]3C[C@]4([H])N([C@](CC4)([H])C3)CC[C@@H](C5=CC(F)=CC=C5)NC(C)=O
Molecular Formula
C29H40FN5O2
Molecular Weight
509.66
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Ya Zhu, et al. Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5. Acta Pharmacol Sin. 2019 Apr;40 (4) :563-568.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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