PF-232798

• UNSPSC Description:

  PF-232798 is an orally active CCR5 antagonist with anti-HIV effects[1].

• Target Antigen:

  CCR; HIV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;GPCR/G Protein;Immunology/Inflammation

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pf-232798.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=NC(CN(CC2)C(C(C)C)=O)=C2N1[C@H]3C[C@]4([H])N([C@](CC4)([H])C3)CC[C@@H](C5=CC(F)=CC=C5)NC(C)=O

• Molecular Weight:

  509.66

• References & Citations:

  [1]Ya Zhu, et al. Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5. Acta Pharmacol Sin. 2019 Apr;40(4):563-568.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  849753-15-7