HER2-IN-7

HER2-IN-7

• CAS Number: 2387574-01-6
• UNSPSC Description: HER2-IN-7 is a potent inhibitor of HER2. Deregulation of ErbB family signalling modulates proliferation, invasion, metastasis, angiogenesis, and tumour cell survival. HER2-IN-7 has the potential for the research of diseases associated ErbBs (especially HER2), including cancer (extracted from patent WO2019214634A1, compound 23)[1].
• Target Antigen: EGFR
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/her2-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=C(OC2C(F)(F)CN(C)CC2)C3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5F)C(C)=C4)N=CN=C3C=C1
• Molecular Weight: 565.55
• References & Citations: [1]Zhengtao LI, et al. Erbb receptor inhibitors. Patent WO2019214634A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported