HER2-IN-7

• Description :

  HER2-IN-7 is a potent inhibitor of HER2. Deregulation of ErbB family signalling modulates proliferation, invasion, metastasis, angiogenesis, and tumour cell survival. HER2-IN-7 has the potential for the research of diseases associated ErbBs (especially HER2), including cancer (extracted from patent WO2019214634A1, compound 23) [1].

• UNSPSC :

  12352005

• Target :

  EGFR

• Type :

  Reference compound

• Related Pathways :

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/her2-in-7.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(OC2C(F)(F)CN(C)CC2)C3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5F)C(C)=C4)N=CN=C3C=C1

• Molecular Formula :

  C28H26F3N7O3

• Molecular Weight :

  565.55

• References & Citations :

  [1]Zhengtao LI, et al. Erbb receptor inhibitors. Patent WO2019214634A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2387574-01-6]