HER2-IN-7

CAT: 0804-HY-143874Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-143874Size:1 Each
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Description
HER2-IN-7 is a potent inhibitor of HER2. Deregulation of ErbB family signalling modulates proliferation, invasion, metastasis, angiogenesis, and tumour cell survival. HER2-IN-7 has the potential for the research of diseases associated ErbBs (especially HER2), including cancer (extracted from patent WO2019214634A1, compound 23) [1].
CAS Number
[2387574-01-6]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/her2-in-7.html
Solubility
10 mM in DMSO
Smiles
COC1=C(OC2C(F)(F)CN(C)CC2)C3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5F)C(C)=C4)N=CN=C3C=C1
Molecular Formula
C28H26F3N7O3
Molecular Weight
565.55
References & Citations
[1]Zhengtao LI, et al. Erbb receptor inhibitors. Patent WO2019214634A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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