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PPARδ agonist 8

CAT: 0804-HY-143863Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143863Size:1 Each
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Description
Pparδ agonist 8 is a potent agonist of Pparδ. The peroxisome proliferator-activated receptor (PPAR) is a member of the intranuclear receptor transcription factor superfamily that plays a key role in the regulation of metabolic homeostasis, inflammation, cell growth and differentiation in vivo. Pparδ agonist 8 has the potential for the research of non-alcoholic fatty liver disease (NAFLD) (extracted from patent WO2021169769A1, compound TM2) [1].
CAS Number
2697129-55-6
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparδ-agonist-8.html
Solubility
10 mM in DMSO
Smiles
CC(C)(OC1=C(C)C=C(CCC(O)C2=CC3=CC=CC=C3N=C2OC)C=C1C)C(O)=O
Molecular Formula
C25H29NO5
Molecular Weight
423.50
References & Citations
[1]Shoujun Chen, et al. Aromatic compounds and pharmaceutical compositions and uses thereof. Patent WO2021169769A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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