HER2-IN-5

• Description :

  HER2-IN-5 is a potent and orally active HER-2 inhibitor, example 10, extracted from patent WO2021164697[1].

• CAS Number :

  [2691891-36-6]

• UNSPSC :

  12352005

• Target :

  EGFR

• Type :

  Reference compound

• Related Pathways :

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/her2-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C2C(N)=NC=CN2C([C@H]3CN(C(C=C)=O)CCC3)=N1)NC4=CC=C(CC(N(C)C)=O)C(C)=C4C

• Molecular Formula :

  C27H33N7O3

• Molecular Weight :

  503.60

• References & Citations :

  [1]Yihan Wang, et al. Substituted amide derivative and composition thereof and use thereof . Patent WO2021164697.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  ErbB2/HER2