HER2-IN-5

• Description:

  HER2-IN-5 is a potent and orally active HER-2 inhibitor, example 10, extracted from patent WO2021164697[1].

• UNSPSC:

  12352005

• Target:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/her2-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C2C(N)=NC=CN2C([C@H]3CN(C(C=C)=O)CCC3)=N1)NC4=CC=C(CC(N(C)C)=O)C(C)=C4C

• Molecular Formula:

  C27H33N7O3

• Molecular Weight:

  503.60

• References & Citations:

  [1]Yihan Wang, et al. Substituted amide derivative and composition thereof and use thereof . Patent WO2021164697.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  ErbB2/HER2

• CAS Number:

  [2691891-36-6]