MK-4965

• Description:

  MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI) . MK-4965 displays excellent activities against not only HIV-1 wild-type (WT) virus but also against a broad panel of NNRTI-resistant viruses and can be used for the research of HIV-1 infection[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  HIV; Reverse Transcriptase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mk-4965.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC(Cl)=CC(OC2=CC(OCC3=NNC4=NC(N)=CC=C43)=CC=C2Cl)=C1

• Molecular Formula:

  C20H13Cl2N5O2

• Molecular Weight:

  426.26

• Precautions:

  P264-P270-P330-P501

• References & Citations:

  [1]Lai MT, et al. Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2009 Jun;53 (6) :2424-31.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  920035-77-4