BChE-IN-5

• Description:

  BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC50 of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bche-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34

• Molecular Formula:

  C30H42N4O

• Molecular Weight:

  474.68

• References & Citations:

  [1]Meden A, et al. Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors. Eur J Med Chem. 2020 Dec 15;208:112766.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AChE; BChE

• CAS Number:

  [2983586-25-8]