Enpp-1-IN-11

Enpp-1-IN-11

• UNSPSC Description: Enpp-1-IN-11 (compound 23) is a potent Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) inhibitor with an Ki value of 45 nM. Enpp-1-IN-11 exhibits low clearance in human and mouse liver microsomes, good plasma stability in human and mouse plasma. Enpp-1-IN-11 can be used for researching anticancer[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/enpp-1-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC(NC(CSC2=NC(N)=CC3=C2NC=N3)=O)=CC=C1O
• Molecular Weight: 345.38
• References & Citations: [1]Gangar M, et al. Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy. Bioorg Chem. 2022 Feb;119:105549.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported