Enpp-1-IN-5

• CAS Number:

  2230916-95-5

• UNSPSC Description:

  Enpp-1-IN-5 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-5 has the potential for the research of cancer and infectious diseases (extracted from patent WO2019046778A1/WO2021203772A1, compound 1)[1][2].

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/enpp-1-in-5.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=S(N)(NCCC1CCN(CC1)C2=C3C=C(OC)C(OC)=CC3=NC(N)=N2)=O

• Molecular Weight:

  410.49

• References & Citations:

  [1]William Michael Gallatin, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof. Patent WO2019046778A1.|[2]Bang Fu, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 inhibitors,compositions and uses thereof. Patent WO2021203772A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported