Enpp-1-IN-13

Enpp-1-IN-13

• CAS Number: 2417022-19-4
• UNSPSC Description: Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC50 values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/enpp-1-in-13.html
• Solubility: 10 mM in DMSO
• Smiles: S=C(NC1=CC=CC=C1)NC2=CC=CC(N3N=C(C4=CC=C(OC)C(Cl)=C4)C(C5=CC=NC=C5)=C3)=C2
• Molecular Weight: 512.03
• References & Citations: [1]Ullah S, et al. Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. Bioorg Chem. 2020 Jun;99:103783.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported