Enpp-1-IN-13

• CAS Number:

  2417022-19-4

• UNSPSC Description:

  Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC50 values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity[1].

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/enpp-1-in-13.html

• Solubility:

  10 mM in DMSO

• Smiles:

  S=C(NC1=CC=CC=C1)NC2=CC=CC(N3N=C(C4=CC=C(OC)C(Cl)=C4)C(C5=CC=NC=C5)=C3)=C2

• Molecular Weight:

  512.03

• References & Citations:

  [1]Ullah S, et al. Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. Bioorg Chem. 2020 Jun;99:103783.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported