Enpp-1-IN-14

• UNSPSC Description:

  Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity[1].

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/enpp-1-in-14.html

• Solubility:

  DMSO : 9.62 mg/mL (ultrasonic)

• Smiles:

  O=S(N)(N1CCN(CCC1)C2=C3C=C(OC)C(OC)=CC3=NC=N2)=O.Cl

• Molecular Weight:

  403.88

• References & Citations:

  [1]Srinivas Rao Kasibhatla, et al. Inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (enpp1) and methods of use thereof. WO2021158829A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2687222-59-7