RORγt modulator 4

• Description:

  RORγt modulator 4 is a RORγt modulator. RORγt modulator 4 has an activity to modulate IL-17A production in cells derived from mouse spleen (WO2018030550A1; compound 146) [1].

• UNSPSC:

  12352005

• Target:

  ROR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rorγt-modulator-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NC2=C(C=C1)N(C3=CC(C4CC4)=CC(C)=C3)CCO2)NCC5=CC=C(S(=O)(C)=O)C=C5

• Molecular Formula:

  C26H27N3O4S

• Molecular Weight:

  477.58

• References & Citations:

  [1]Satoshi Yamamoto, et al. Heterocyclic compounds with an ror (gamma) t modulating activity. WO2018030550A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  RORγ

• CAS Number:

  [2188177-73-1]