MAT2A-IN-3

• Description:

  MAT2A-IN-3 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-3 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has the potential for the research of cancer diseases (extracted from patent WO2019191470A1, compound 265) [1].

• UNSPSC:

  12352005

• Target:

  Somatostatin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mat2a-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C (C2=CC=C (OC (F) F) C=C2) =C3N=C (OCC (F) (F) F) N=CC3=CN1C4=CC5=CN (C) N=C5C=C4

• Molecular Formula:

  C24H16F5N5O3

• Molecular Weight:

  517.41

• References & Citations:

  [1]Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2019191470A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2377493-28-0