Products for Research Use Only
RegisterLogin

Lp-PLA2-IN-11

CAT: 0804-HY-142779Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-142779Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) . Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) [1].
CAS Number
1620680-19-4
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lp-pla2-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(OCC2=CC=C(OC3=CC=C(C(F)(F)F)N=C3)C(F)=C2)C=C4N(C)[C@H](C)CCN41
Molecular Formula
C22H20F4N4O3
Molecular Weight
464.41
References & Citations
[1]Zehong Wan, et al. Bicyclic pyrimidone compounds as inhibitors of lp-pla2. Patent WO2014114249A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-19757-01Lp-PLA2-IN-1
HY-133149-01Lp-PLA2-IN-3
HY-142670Lp-PLA2-IN-5
HY-142777Lp-PLA2-IN-9
HY-142778Lp-PLA2-IN-10
HY-153183Lp-PLA2-IN-12
HY-153560Lp-PLA2-IN-14
HY-153559-01Lp-PLA2-IN-13
HY-153561ALp-PLA2-IN-16
HY-142774Lp-PLA2-IN-6

Alternative Products

CatalogName
T62947-01Lp-PLA2-IN-11
MBS344255-01Lp-PLA2
BA8258-5Lp-PLA2-IN-3
30-1992Lp-PLA2 Protein
10-2748Lp-PLA2 antibody
T86821-01Lp-PLA2-IN-17
T11873-01Lp-PLA2-IN-2
T63633-01Lp-PLA2-IN-6
MBS3615359-01Lp-PLA2-IN-1
MBS5820735Lp-PLA2-IN-14

Popular Products