BChE-IN-2

• Description :

  BChE-IN-2 (compound 22) is a potent inhibitor of BChE with a Ki of 0.099 μM. BChE-IN-2 is a pyrimidine and pyridine derivative. BChE-IN-2 has the potential for the research of Alzheimer’s disease (AD) [1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/bche-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C1(NCCCCCCCCCNCC2=CNC3=C2C=CC=C3)=NC=CC=N1

• Molecular Formula :

  C22H31N5

• Molecular Weight :

  365.52

• References & Citations :

  [1]Bortolami M, et al. New Pyrimidine and Pyridine Derivatives as Multitarget Cholinesterase Inhibitors: Design, Synthesis, and In Vitro and In Cellulo Evaluation. ACS Chem Neurosci. 2021;12 (21) :4090-4112.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported