BChE-IN-2

• UNSPSC Description:

  BChE-IN-2 (compound 22) is a potent inhibitor of BChE with a Ki of 0.099 μM. BChE-IN-2 is a pyrimidine and pyridine derivative. BChE-IN-2 has the potential for the research of Alzheimer’s disease (AD) [1].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bche-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C1(NCCCCCCCCCNCC2=CNC3=C2C=CC=C3)=NC=CC=N1

• Molecular Weight:

  365.52

• References & Citations:

  [1]Bortolami M, et al. New Pyrimidine and Pyridine Derivatives as Multitarget Cholinesterase Inhibitors: Design, Synthesis, and In Vitro and In Cellulo Evaluation. ACS Chem Neurosci. 2021;12(21):4090-4112.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported