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PI3Kγ inhibitor 5

CAT: 0804-HY-139880Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139880Size:1 Each
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Description
PI3Kγ inhibitor 5 is an inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with an IC50 value of 34 nM.
CAS Number
2566569-31-9
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kγ-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2N=C(C3=CC4=C(C(N([C@H](C5CC5)C)C4)=O)C(OC(F)F)=C3)C=CN2N=C1N)N[C@H]6CC[C@@](C)(O)CC6
Molecular Formula
C28H32F2N6O4
Molecular Weight
554.59
References & Citations
[1]Mata G, et al. Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ) . J Med Chem. 2021 Oct 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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