PI3Kγ inhibitor 5

• UNSPSC Description:

  PI3Kγ inhibitor 5 is an inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with an IC50 value of 34 nM.

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3kγ-inhibitor-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C2N=C(C3=CC4=C(C(N([C@H](C5CC5)C)C4)=O)C(OC(F)F)=C3)C=CN2N=C1N)N[C@H]6CC[C@@](C)(O)CC6

• Molecular Weight:

  554.59

• References & Citations:

  [1]Mata G, et al. Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ). J Med Chem. 2021 Oct 21.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2566569-31-9