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PI3kδ inhibitor 1

CAT: 0804-HY-15288Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15288Size:1 Each
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Description
PI3kδ inhibitor 1 is a potent and selective PI3Kδ inhibitor with an IC50 of 3.8 nM.
CAS Number
1332075-63-4
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k_delta_-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
CC(O)(C1CCN(CC2=NC3=C(N4CCOCC4)N=C(C5=C(F)C=CC6=C5C=CN6)N=C3C=C2)CC1)C
Molecular Formula
C28H33FN6O2
Molecular Weight
504.60
References & Citations
[1]Sutherlin DP, et al. Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf. Bioorg Med Chem Lett. 2012 Jul 1;22 (13) :4296-302.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kδ

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