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PI3K-α Inhibitor

CAT: 0026-B1869-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1869-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3Kα inhibitor is a potent and selective inhibitor of PI3Kα with IC₅₀ values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It inhibits PKA, KDR, PKCα, and cyclin E/Cdk2 significantly less effectively (IC₅₀ = 91, 3.4, 466, and 28 µM, respectively). PI3Kα inhibitor inhibits A375 melanoma cell proliferation with an IC₅₀ value of 580 nM.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months

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