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PLK1-IN-2

CAT: 0804-HY-139652Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139652Size:1 Each
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Description
PLK1-IN-2 is a PLK1 kinase inhibitor with an IC50 value of 0.384 μM.
CAS Number
2640254-52-8
UNSPSC
12352005
Target
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plk1-in-2.html
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCN1C2=CC=C(NC3=NC(N(C4=NC(N=S(C)(C)=O)=CC=C4)C=C5F)=C5C=N3)C=C2
Molecular Formula
C24H27FN8OS
Molecular Weight
494.59
References & Citations
[1]Kargbo RB. Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics. ACS Med Chem Lett. 2021 Sep 15;12 (10) :1514-1516.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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