PLK1-IN-2

• UNSPSC Description:

  PLK1-IN-2 is a PLK1 kinase inhibitor with an IC50 value of 0.384 μM.

• Target Antigen:

  Polo-like Kinase (PLK)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/plk1-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN(CC1)CCN1C2=CC=C(NC3=NC(N(C4=NC(N=S(C)(C)=O)=CC=C4)C=C5F)=C5C=N3)C=C2

• Molecular Weight:

  494.59

• References & Citations:

  [1]Kargbo RB. Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics. ACS Med Chem Lett. 2021 Sep 15;12(10):1514-1516.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2640254-52-8