Products for Research Use Only
RegisterLogin

PLK1-IN-4

CAT: 0804-HY-146792Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-146792Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PLK1-IN-4 is a potent and selective PLK1 inhibitor with IC50 apoptosis. PLK1-IN-4 can be used for researching hepatocellular carcinoma[1].
CAS Number
2622273-55-4
UNSPSC
12352005
Target
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plk1-in-4.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C2C(CCN2C(CN(C)C)=O)=C1)NC3=NC=C(C(NC4=C(SC=C4)C(OC)=O)=N3)C(F)(F)F
Molecular Formula
C24H25F3N6O4S
Molecular Weight
550.55
References & Citations
[1]Deng Z, et al. Discovery of methyl 3- ((2- ((1- (dimethylglycyl) -5-methoxyindolin-6-yl) amino) -5- (trifluoro-methyl) pyrimidin-4-yl) amino) thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma. Eur J Med Chem. 2020;206:112697.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-172364PLK1-IN-12
HY-173233PLK1-IN-14
HY-169579-01PLK1-IN-11
HY-148974PLK1-IN-5
HY-161046PLK1-IN-8
HY-173212PLK1-IN-13
HY-139652PLK1-IN-2
HY-172880PLK1-IN-15
HY-156336PLK1-IN-7
HY-149100PLK1-IN-6

Alternative Products

CatalogName
BUP24075-01PLK1-IN-4
527088-01PLK1
10R-5318PLK1 antibody
T208795-01PLK1-IN-8
MBS517420-01PLK1, Active

Popular Products