PLK1-IN-7

CAT: 0804-HY-156336Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-156336Size:1 Each

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Description

PLK1-IN-7 (compound 30e) is a potent PLK1 inhibitor, with an IC50 of 0.66 nM. PLK1-IN-7 exhibits antiproliferative and antitumor activities[1].

CAS Number

2938910-96-2

UNSPSC

12352005

Target

Polo-like Kinase (PLK)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/plk1-in-7.html

Solubility

10 mM in DMSO

Smiles

FC(F)(OC(C=CC(N1CCN(C)CC1)=C2)=C2NC3=NC=C4C(C5=C(C=C4)C(C(N)=O)=NN5CCF)=N3)F

Molecular Formula

C24H24F4N8O2

Molecular Weight

532.49

References & Citations

[1]Lu J, et, al. Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1. Bioorg Chem. 2023 Oct:139:106711.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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