PLK1-IN-7

• UNSPSC Description:

  PLK1-IN-7 (compound 30e) is a potent PLK1 inhibitor, with an IC50 of 0.66 nM. PLK1-IN-7 exhibits antiproliferative and antitumor activities[1].

• Target Antigen:

  Polo-like Kinase (PLK)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/plk1-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(F)(OC(C=CC(N1CCN(C)CC1)=C2)=C2NC3=NC=C4C(C5=C(C=C4)C(C(N)=O)=NN5CCF)=N3)F

• Molecular Weight:

  532.49

• References & Citations:

  [1]Lu J, et, al. Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1. Bioorg Chem. 2023 Oct:139:106711.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2938910-96-2