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DdCTP (trilithium)

CAT: 0804-HY-137697BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137697BSize:1 Each
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Description
DdCTP trilithium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP trilithium is a nucleoside analog that targets the reverse trsanscriptase of human immunodeficiency virus (HIV) . ddCTP trilithium can be used for AIDS research[1][2].
CAS Number
93939-77-6
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
DNA/RNA Synthesis; HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ddctp-trilithium.html
Solubility
10 mM in DMSO
Smiles
O=[P](O[P](O[P](O)(O[Li])=O)(O[Li])=O)(O[Li])OC[C@@H]1CC[C@H](N2C(N=C(N)C=C2)=O)O1
Molecular Formula
C9H13Li3N3O12P3
Molecular Weight
468.96
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Z G Chidgeavadze, et al. 3'-Fluoro-2',3'-dideoxyribonucleoside 5'-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183 (2) :275-8.|[2]Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264 (5167) :1891-903.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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