ddCTP (trilithium)

ddCTP (trilithium)

• CAS Number: 93939-77-6
• UNSPSC Description: ddCTP trilithium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP trilithium is a nucleoside analog that targets the reverse trsanscriptase of human immunodeficiency virus (HIV). ddCTP trilithium can be used for AIDS research[1][2].
• Target Antigen: DNA/RNA Synthesis; HIV Protease
• Type: Reference compound
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/ddctp-trilithium.html
• Solubility: 10 mM in DMSO
• Smiles: O=[P](O[P](O[P](O)(O[Li])=O)(O[Li])=O)(O[Li])OC[C@@H]1CC[C@H](N2C(N=C(N)C=C2)=O)O1
• Molecular Weight: 468.96
• References & Citations: [1]Z G Chidgeavadze, et al. 3'-Fluoro-2',3'-dideoxyribonucleoside 5'-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183(2):275-8.|[2]Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264(5167):1891-903.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported