DdCTP

CAT: 0804-HY-137697Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-137697Size:1 Each
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Description
DdCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP is a nucleoside analog that targets the reverse transcriptase of HIV. ddCTP can be used for AIDS research[1][2].
CAS Number
[66004-77-1]
UNSPSC
12352200
Hazard Statement
H315-H319-H335
Target
DNA/RNA Synthesis; HIV Protease
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
O=[P](O[P](O[P](O)(O)=O)(O)=O)(O)OC[C@@H]1CC[C@H](N2C(N=C(N)C=C2)=O)O1
Molecular Formula
C9H16N3O12P3
Molecular Weight
451.16
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Z G Chidgeavadze, et al. 3'-Fluoro-2',3'-dideoxyribonucleoside 5'-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183 (2) :275-8.|[2]Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264 (5167) :1891-903.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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