Hexanoyl coenzyme A (trilithium)

• Description:

  Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD) [1][2].

• UNSPSC:

  12352204

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Endogenous Metabolite

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/hexanoyl-coenzyme-a-trilithium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@] (O[C@@H] ([C@H]1OP (O) (O) =O) COP (OP (OCC (C) (C) [C@@H] (O) C (NCCC (NCCSC (CCCCC) =O) =O) =O) (O) =O) (O) =O) ([H]) N2C3=NC=NC (N) =C3N=C2.[Li].[Li].[Li]

• Molecular Formula:

  C27H46Li3N7O17P3S

• Molecular Weight:

  886.50

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Jake M Stout, et al. The hexanoyl-CoA precursor for cannabinoid biosynthesis is formed by an acyl-activating enzyme in Cannabis sativa trichomes. Plant J. 2012 Aug;71 (3) :353-65.|[2]K E Niezen-Koning, et al. Measurement of short-chain acyl-CoA dehydrogenase (SCAD) in cultured skin fibroblasts with hexanoyl-CoA as a competitive inhibitor to eliminate the contribution of medium-chain acyl-CoA dehydrogenase. Clin Chim Acta. 1994 Sep;229 (1-2) :99-106.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Enzyme

• Clinical Information:

  No Development Reported

• CAS Number:

  103476-19-3