Products for Research Use Only
RegisterLogin

DHODH-IN-14

CAT: 0804-HY-135678Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-135678Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DHODH-IN-14 (Compound 7l) is a hydroxyfurazan analog of A771726. DHODH-IN-14 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.49 μM for rat liver DHODH. DHODH-IN-14 can be used for rheumatoid arthritis[1].
CAS Number
1364791-93-4
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dhodh-in-14.html
Purity
99.81
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(C1=NONC1=O)NC2=C(F)C(F)=C(C3=CC=CC=C3)C(F)=C2F
Molecular Formula
C15H7F4N3O3
Molecular Weight
353.23
References & Citations
[1]Lolli ML, et al. New inhibitors of dihydroorotate dehydrogenase (DHODH) based on the 4-hydroxy-1,2,5-oxadiazol-3-yl (hydroxyfurazanyl) scaffold. Eur J Med Chem. 2012 Mar;49:102-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-135618DHODH-IN-3
HY-135676DHODH-IN-12
HY-179531DHODH-IN-33
HY-135662DHODH-IN-34
HY-163158DHODH-IN-24
HY-158023DHODH-IN-26
HY-163328DHODH-IN-25
HY-128068-01DHODH-IN-17
HY-149030DHODH-IN-21
HY-135619DHODH-IN-4

Alternative Products

CatalogName
BUP12042-01DHODH-IN-14
560330-01DHODH
BA3997-5.1DHODH-IN-16
BA7297-50DHODH-IN-23
BA7296-5DHODH-IN-17
70R-6503DHODH antibody
T211423-01DHODH-IN-29
T11026-01DHODH-IN-3
T11030-01DHODH-IN-8
T11024-01DHODH-IN-15

Popular Products