DHODH-IN-34

• Description:

  DHODH-IN-34 (Compound 21q) is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 13 nM. DHODH-IN-34 is promising for research of RNA viruses such as measles virus and chikungunya virus[1].

• UNSPSC:

  12352005

• Target:

  Dihydroorotate Dehydrogenase

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Smiles:

  CCC1=CN=C(N2N=C(OC(C)C)C(OC3=C(F)C=CC=C3F)=C2C)N=C1

• Molecular Formula:

  C19H20F2N4O2

• Molecular Weight:

  374.38

• References & Citations:

  [1]Munier-Lehmann H, et al. Original 2- (3-alkoxy-1H-pyrazol-1-yl) pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH) . J Med Chem. 2015 Jan 22;58 (2) :860-77.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1644156-93-3]