Products for Research Use Only

DHODH-IN-8

CAT: 0931-T11030-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0931-T11030-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1148126-03-7
Target
Parasite, Dehydrogenase, DNA/RNA Synthesis
Related Pathways
Metabolism, Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9978
Bioactivity
DHODH-IN-8 has antimalarial activity. DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively.
Smiles
ClC1=C(C2=CC=C(NC(/C(=C(/C)\O)/C#N)=O)C=C2)C=CC=C1
Molecular Formula
C17H13ClN2O2
Molecular Weight
312.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C