PF-06371900

• Description :

  PF-06371900 is a potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor[1].

• UNSPSC :

  12352005

• Target :

  LRRK2

• Type :

  Reference compound

• Related Pathways :

  Autophagy

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/pf-06371900.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN1N=CC(C2=NN=C3C=CC(SC4=CC(OC)=CC=C4OC)=NN32)=C1

• Molecular Formula :

  C17H16N6O2S

• Molecular Weight :

  368.41

• References & Citations :

  [1]Henderson JL, et al. Discovery and preclinical profiling of 3-[4- (morpholin-4-yl) -7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58 (1) :419-32.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1622291-81-9]