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Nav1.8-IN-1

CAT: 0804-HY-132133Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132133Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nav1.8-IN-1 (Compound 31) is a potent inhibitor of Na (v) 1.8 sodium channel. Nav1.8-IN-1 has the potential for the research of inflammatory and neuropathic pain[1].
CAS Number
1026822-49-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=CC=C(Cl)C=C2)=CN=C1)NCC3=CC=CN=C3OCC(F)(F)F
Molecular Formula
C20H15ClF3N3O2
Molecular Weight
421.80
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Kort ME, et al. Subtype-selective Na (v) 1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorg Med Chem Lett. 2010;20 (22) :6812-6815.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.8

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