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DMAC-SPDB

CAT: 0931-T40764Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T40764Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
663599-05-1
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DMAC-SPDB is a cleavable linker vital in ADC synthesis. DMAC-SPDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
Smiles
CN(C)C(=O)c1ccc(SSCCCC(=O)ON2C(=O)CCC2=O)nc1
Molecular Formula
C16H19N3O5S2
Molecular Weight
397.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

2,5-Dioxopyrrolidin-1-yl 4-((5-(dimethylcarbamoyl)pyridin-2-yl)disulfanyl)butanoate
CAS Number663599-05-1
PubChem CID118797506
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 4-[[5-(dimethylcarbamoyl)-2-pyridinyl]disulfanyl]butanoate
Molecular FormulaC16H19N3O5S2
Molecular Weight397.5
XLogP0.5
Topological Polar Surface Area147
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Heavy Atom Count26
Formal Charge0
Complexity542
SMILES
CN(C)C(=O)C1=CN=C(C=C1)SSCCCC(=O)ON2C(=O)CCC2=O
InChI
InChI=1S/C16H19N3O5S2/c1-18(2)16(23)11-5-6-12(17-10-11)26-25-9-3-4-15(22)24-19-13(20)7-8-14(19)21/h5-6,10H,3-4,7-9H2,1-2H3
InChIKey
XDZYHHAHYBOELZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2,5-Dioxopyrrolidin-1-yl 4-((5-(dimethylcarbamoyl)pyridin-2-yl)disulfanyl)butanoate
CAS: 663599-05-1
CID: 118797506
Formula: C16H19N3O5S2
MW: 397.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight397.5
XLogP30.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass397.07661306
Monoisotopic Mass397.07661306
Topological Polar Surface Area147 Ų
Heavy Atom Count26
Formal Charge0
Complexity542
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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