SHP2-IN-5

• Description :

  SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC50: 97 nM) . SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases[1].

• UNSPSC :

  12352005

• Target :

  SHP2

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/shp2-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC1=CC=C(C=C(C(O)=O)C=C(O)C2=O)C2=C1O

• Molecular Formula :

  C12H8O6

• Molecular Weight :

  248.19

• References & Citations :

  [1]Kim B, et al. Development and structure-activity relationship study of SHP2 inhibitor containing 3, 4, 6-trihydroxy-5-oxo-5H-benzo [7] annulene[J]. Bioorganic & Medicinal Chemistry Letters, 2020, 30 (1) : 126756.. . .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [54755-93-0]