Products for Research Use Only
RegisterLogin

SHP2-IN-8

CAT: 0931-T61891-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T61891-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1801692-60-3
Target
Others, Phosphatase, Apoptosis, Akt
Related Pathways
Cytoskeletal Signaling, Metabolism, Others, Apoptosis, PI3K/Akt/mTOR signaling
Bioactivity
SHP2-IN-8 is a reversible, noncompetitive, selective and efficient allosteric SHP2 inhibitor (IC50=23 nM, Ki=22 nM), which also has effects in cells. SHP2-IN-8 can cause significant thermal displacement (Δ Tm = 7.01 °C) . SHP2-IN-8 can inhibit the phosphorylation of AKT and induce apoptosis of Hela cells.
Smiles
NC=1N=C(N2CCC(CN)(C)CC2)C=NC1SC3=C(Cl)C(Cl)=CC=C3
Molecular Formula
C17H21Cl2N5S
Molecular Weight
398.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T210874-01SHP2-IN-40
T209308-01SHP2-IN-26
T207602-01SHP2-IN-37
T81165-01SHP2-IN-17
T81161-01SHP2-IN-21
T40121SHP2-D26
T212530-01SHP2-IN-42
T212248-01SHP2-IN-43
T211063-01SHP2-IN-39
T209771-01SHP2-IN-28

Alternative Products

CatalogName
HY-144396SHP2-IN-8
E8ET1611-80SHP2
GTR18078133SHP2 Antibody
BA8113-5SHP2-IN-9
HY-176796SHP2-IN-43
HY-145162-01SHP2-D26
HY-155276SHP2-IN-20
HY-155273SHP2-IN-17
HY-175520SHP2-IN-42
HY-172911-01SHP2-IN-37

Popular Products