SHP2-IN-20

• Description :

  SHP2-IN-20 (compound 193) is a SHP2 inhibitor with an IC50 value of 3 nM. SHP2-IN-20 can be used for glioblastoma research[1].

• UNSPSC :

  12352005

• Target :

  SHP2

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/shp2-in-20.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC1=CC(F)=CC=C1C2=C(C)N=C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)C6=CC=NN26

• Molecular Formula :

  C25H24F2N6

• Molecular Weight :

  446.50

• References & Citations :

  [1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14 (10) :1336-1337.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2941498-94-6]