EUK-118

CAT: 0804-HY-130438Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-130438Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EUK-118 is an analog of EUK 8 and EUK 134 with reduced activity. EUK-118 exhibits superoxide dismutase (SOD) mimetic activity[1][2].
CAS Number
[186299-34-3]
UNSPSC
12352300
Target
SOD
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/euk-118.html
Solubility
10 mM in DMSO
Smiles
CC([O-][Mn+3]123[N](CC[N]2=CC4=C(OC)C=C(OC)C=C4[O-]3)=CC5=C(C=C(OC)C=C5OC)[O-]1)=O
Molecular Formula
C22H25MnN2O8
Molecular Weight
500.38
References & Citations
[1]Doctrow SR, et, al. Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies. J Med Chem. 2002 Sep 26;45 (20) :4549-58.|[2]Vera M, et, al. Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease. Cell Physiol Biochem. 2018;51 (3) :1287-1300.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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