RegisterLogin

EUK-134

CAT: 0804-HY-100594-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100594-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase (SOD) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB, MDA level, and protein carbonylation in H9C2 cells[1][2][3].
CAS Number
[81065-76-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/euk-134.html
Purity
98.27
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
COC1=CC=CC2=C1[O-][Mn+3]([Cl-])[O-]C(C(OC)=CC=C3)=C3/C=N/CC/N=C/2
Molecular Formula
C18H18ClMnN2O4
Molecular Weight
416.74
Precautions
H302, H315, H319, H335
References & Citations
[1]P Gianello, et al. EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. Transplantation. 1996 Dec 15;62 (11) :1664-6.|[2]Mohamed Samai, et al. Comparison of the effects of the superoxide dismutase mimetics EUK-134 and tempol on paraquat-induced nephrotoxicity. Free Radic Biol Med. 2007 Aug 15;43 (4) :528-34.|[3]Sreeja Purushothaman, et al. Mitoprotective antioxidant EUK-134 stimulates fatty acid oxidation and prevents hypertrophy in H9C2 cells. Mol Cell Biochem. 2016 Sep;420 (1-2) :185-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NF-κB

Related Products

CatalogName
HY-130438EUK-118
HY-130439-01EUK-124
HY-19382EUK-189
HY-141810MT-134
HY-168623EGFR-IN-134
HY-156996AGI-134
HY-13312AGTx-134
HY-119306MCC-134
HY-172940TBP-134
HY-D0351-01Fluorescent Brightener 134

Alternative Products

CatalogName
sc-205321AEUK 134
2175-5EUK-134
T22772-01EUK 118
2174-25EUK-124
T22773-01EUK 124
2173-25EUK-118

Popular Products