RTI-118

• Description:

  RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration[1].

• UNSPSC:

  12352005

• Target:

  Neuropeptide Y Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/rti-118.html

• Concentration:

  10mM

• Purity:

  99.90

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C (N1CC2N (C (OC2 (C3=CC=CC=C3) C4=CC=CC=C4) =O) CC1) NCCN5CCCCC5

• Molecular Formula:

  C26H32N4O3

• Molecular Weight:

  448.56

• References & Citations:

  [1]Schmoutz CD, et al.Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats.Pharmacol Biochem Behav. 2012 Dec;103 (2) :332-7.|[2]Bonano JS, et al. Effects of the neuropeptide S receptor antagonist RTI-118

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  847554-50-1