RTI-118

• UNSPSC Description:

  RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration[1].

• Target Antigen:

  Neuropeptide Y Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/rti-118.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CC2N(C(OC2(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1)NCCN5CCCCC5

• Molecular Weight:

  448.56

• References & Citations:

  [1]Schmoutz CD, et al.Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats.Pharmacol Biochem Behav. 2012 Dec;103(2):332-7.|[2]Bonano JS,et al. Effects of the neuropeptide S receptor antagonist RTI-118

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  847554-50-1