RTI-118

• Description :

  RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration[1].

• UNSPSC :

  12352005

• Target :

  Neuropeptide Y Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/rti-118.html

• Concentration :

  10mM

• Purity :

  99.90

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  O=C(N1CC2N(C(OC2(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1)NCCN5CCCCC5

• Molecular Formula :

  C26H32N4O3

• Molecular Weight :

  448.56

• References & Citations :

  [1]Schmoutz CD, et al.Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats.Pharmacol Biochem Behav. 2012 Dec;103 (2) :332-7.|[2]Bonano JS, et al. Effects of the neuropeptide S receptor antagonist RTI-118

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [847554-50-1]