PD 132002

CAT: 0804-HY-129695Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-129695Size:1 Each

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Description

PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure[1].

CAS Number

134452-04-3

UNSPSC

12352005

Target

Renin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pd-132002.html

Solubility

10 mM in DMSO

Smiles

O=C(C(NC([C@@H](NS(=O)(N1CCOCC1)=O)CC2=CC=CC=C2)=O)C(OC)=O)N[C@H]([C@@H](O)[C@@H](O)CC(C)C)CC3CCCCC3

Molecular Formula

C31H50N4O9S

Molecular Weight

654.82

References & Citations

[1]J T Repine, et al. Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate. J Med Chem. 1991 Jul;34 (7) :1935-43.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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MBS5778018	PD 132002

PD 132002

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