PD-1/PD-L1-IN 5 (TFA)

PD-1/PD-L1-IN 5 (TFA)

• CAS Number: 2170209-52-4
• UNSPSC Description: PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].
• Target Antigen: PD-1/PD-L1
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: N#CC1=C(NC(C2=NC3=C(CNCC3)S2)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4.OC(C(F)(F)F)=O.[x]
• References & Citations: [1]Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported