2-Hydroxy Ibuprofen

• Description :

  2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

• Product Name Alternative :

  (±) -2-Hydroxy Ibuprofen

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H335

• Target :

  COX

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/2-hydroxy-ibuprofen.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1

• Molecular Formula :

  C13H18O3

• Molecular Weight :

  222.28

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

• References & Citations :

  [1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61 (1) :2-7.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [51146-55-5]