2-Hydroxy Ibuprofen

• UNSPSC Description:

  2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

• Target Antigen:

  COX

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/2-hydroxy-ibuprofen.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1

• Molecular Weight:

  222.28

• References & Citations:

  [1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  51146-55-5