Ibuprofen (Standard)

CAT: 0804-HY-78131R-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-78131R-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ibuprofen (Standard) is the analytical standard of Ibuprofen. This product is intended for research and analytical applications. Ibuprofen ((±) -Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±) -Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][5][8].
CAS Number
[15687-27-1]
Product Name Alternative
(±) -Ibuprofen (Standard)
UNSPSC
12352005
Hazard Statement
H302, H319, H335
Target
Apoptosis; COX; Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ibuprofen-standard.html
Purity
99.95
Smiles
OC(C(C1=CC=C(CC(C)C)C=C1)C)=O
Molecular Formula
C13H18O2
Molecular Weight
206.28
Precautions
H302, H319, H335
References & Citations
[1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61 (1) :2-7.|[2]Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36 (5) :3237-43.|[3]Sharon M Rymut, et al. Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311 (2) :L317-27.|[4]Emmanuelle Bignon, et al. Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process. Sci Rep. 2017 Aug 21;7 (1) :8885.|[5]Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6 (1) :98.|[6]Thomas Krøigård, et al. Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy. Exp Brain Res. 2019 Oct;237 (10) :2645-2651.|[7]Sarah Ilkhanipour Rooney, et al. Ibuprofen Differentially Affects Supraspinatus Muscle and Tendon Adaptations to Exercise in a Rat Model. Am J Sports Med. 2016 Sep;44 (9) :2237-45.|[8]M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141 (1) :186-92.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-131261RIbuprofen alcohol (Standard)
HY-78131CR-01Ibuprofen (sodium) (Standard)
HY-101482R-01Ibuprofen piconol (Standard)
HY-131259R-01Ibuprofen Impurity F (Standard)
HY-100586R-01Ibuprofen (L-lysine) (Standard)
HY-131260RIbuprofen Impurity K (Standard)
HY-78131-01Ibuprofen
HY-78131B-01(R) - (-) -Ibuprofen
HY-78131S-01Ibuprofen-d3
HY-78131C-01Ibuprofen (sodium)

Alternative Products

CatalogName
RM-I210400-01Ibuprofen

Popular Products