X-34

• Description :

  X-34 is a lipophilic and bright yellow-green fluorescent derivative of Congo red (HY-D0236) . X-34 can be used to stain neuritic and diffuse plaques, neurofibrillary tangles (NFTs), neuropil threads, and cerebrovascular amyloid in the brain. X-34 can be used for research of Alzheimer’s disease[1].

• CAS Number :

  [215294-98-7]

• UNSPSC :

  12171500

• Target :

  Amyloid-β; Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Neuronal Signaling; Others

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/x-34.html

• Purity :

  96.47

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C1=C(O)C=CC(/C=C/C2=CC=C(/C=C/C3=CC(C(O)=O)=C(O)C=C3)C=C2)=C1

• Molecular Formula :

  C24H18O6

• Molecular Weight :

  402.40

• References & Citations :

  [1]Styren SD, et al. X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology. J Histochem Cytochem. 2000 Sep;48 (9) :1223-32.|[2]Link CD, et al. Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34. Neurobiol Aging. 2001 Mar-Apr;22 (2) :217-26.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported