PF-184298

CAT: 0804-HY-123322-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-123322-01Size:1 mg
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Description
PF-184298 is a dual serotonin/noradrenaline reuptake inhibitor with IC50 of 6 nM and 21 nM, respectively[1].
CAS Number
[813447-40-4]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pf-184298.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(Cl)=C1Cl)N([C@@H]2CNCC2)CC(C)C
Molecular Formula
C15H20Cl2N2O
Molecular Weight
315.24
References & Citations
[1]Anthony Harrison , et al. Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms. Clinical Trial Xenobiotica. 2012 Jan;42 (1) :57-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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