PF-184298

• Description:

  PF-184298 is a dual serotonin/noradrenaline reuptake inhibitor with IC50 of 6 nM and 21 nM, respectively[1].

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/pf-184298.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (C1=CC=CC (Cl) =C1Cl) N ([C@@H]2CNCC2) CC (C) C

• Molecular Formula:

  C15H20Cl2N2O

• Molecular Weight:

  315.24

• References & Citations:

  [1]Anthony Harrison , et al. Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms. Clinical Trial Xenobiotica. 2012 Jan;42 (1) :57-74.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  813447-40-4