PF-184298

• Description :

  PF-184298 is a dual serotonin/noradrenaline reuptake inhibitor with IC50 of 6 nM and 21 nM, respectively[1].

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/pf-184298.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=CC(Cl)=C1Cl)N([C@@H]2CNCC2)CC(C)C

• Molecular Formula :

  C15H20Cl2N2O

• Molecular Weight :

  315.24

• References & Citations :

  [1]Anthony Harrison , et al. Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms. Clinical Trial Xenobiotica. 2012 Jan;42 (1) :57-74.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [813447-40-4]