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3289-8625

CAT: 0804-HY-102067-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-102067-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3289-8625 is an inhibitor of the PDZ domain of Dishevelled (Dvl) protein (Kd=10.6 μM) and has an inhibitory effect on Wnt signaling. In addition, 3289-8625 can slow the growth of prostate cancer PC-3 cells (IC50=12.5 μM) . 3289-8625 can be used in the study of embryonic development and cancer[1].
CAS Number
294891-81-9
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3289-8625.html
Purity
99.19
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=CC=C1NC(C2=CC=CC(NC(CC3=CC=CC=C3)=O)=C2)=O
Molecular Formula
C22H18N2O4
Molecular Weight
374.39
References & Citations
[1]Grandy D, et al. Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled[J]. Journal of Biological Chemistry, 2009, 284 (24) : 16256-16263.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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