Autophagy-IN-3

• UNSPSC Description:

  Autophagy-IN-3 (Compound 6k) is an autophagy inhibitor. Autophagy-IN-3 promotes metabolic stress in the tumor microenvironment and enhances the effects of cytostatics in combined treatments[1].

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/autophagy-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(Cl)=CC=C1O)N[C@H](CC2=CC=CC=C2)C(NC3=CC=C(C=C3)Cl)=O

• Molecular Weight:

  429.30

• References & Citations:

  [1]Páchniková G, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux. Toxicol In Vitro. 2016 Dec;37:70-78.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1227476-98-3