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BRD4 Inhibitor-16

CAT: 0804-HY-115926Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115926Size:1 Each
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Description
BRD4 Inhibitor-16 (Compound 4) is a potent inhibitor of bromodomain 4 (BRD4) . Overexpression of bromodomain 4 (BRD4) is closely correlated with a variety of human cancers by regulating the histone post-translational modifications. BRD4 Inhibitor-16 represents a useful tool for explorative studies of BRD4 inhibition, such as an improved understanding of BRD4 inhibitor release-related information[1].
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-inhibitor-16.html
Solubility
10 mM in DMSO
Smiles
CC1=NOC(C)=C1C2=CC=C3C(C(N(C(N3C)=O)CC(NCCNS(=O)(C4=C5C=CC=C6C(N(C(C(C=C4)=C65)=O)CCN7CCOCC7)=O)=O)=O)C8=CC=CC=C8)=C2
Molecular Formula
C42H43N7O8S
Molecular Weight
805.90
References & Citations
[1]Zhang H, et al. Activatable fluorescence molecular imaging and anti-tumor effects investigation of GSH-sensitive BRD4 ligands [published online ahead of print, 2022 Jan 25]. Bioorg Chem. 2022;120:105636.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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