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BRD4 Inhibitor-17

CAT: 0804-HY-145909Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145909Size:1 Each
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Description
BRD4 Inhibitor-17 (Compound 5i) is a potent inhibitor of BRD4 with an IC50 of 0.33 μM. BRD4 Inhibitor-17 plays crucial role in regulating transcription of inflammatory, proliferation and cell cycle genes. BRD4 Inhibitor-17 serves as potential antidotes for arsenicals[1].
CAS Number
2835555-10-5
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-inhibitor-17.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(S(=O)(NC2=CC3=C(NC(N(C3)C)=O)C=C2)=O)=CC=C1F
Molecular Formula
C16H16FN3O3S
Molecular Weight
349.38
References & Citations
[1]Yatchang MF, et al. Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals. Bioorg Med Chem Lett. 2022;64:128696.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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