CP-67804

• Description:

  CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent[1].

• UNSPSC:

  12352005

• Target:

  Topoisomerase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cp-67804.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN(CC)C2=C(C=C(F)C(C3=CC=C(O)C=C3)=C2F)C1=O)O

• Molecular Formula:

  C18H13F2NO4

• Molecular Weight:

  345.30

• References & Citations:

  [1]Robinson MJ, et al. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991;266 (22) :14585-14592.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Topo II

• CAS Number:

  [103978-08-1]