CP-67804

• Description :

  CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent[1].

• UNSPSC :

  12352005

• Target :

  Topoisomerase

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cp-67804.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CN(CC)C2=C(C=C(F)C(C3=CC=C(O)C=C3)=C2F)C1=O)O

• Molecular Formula :

  C18H13F2NO4

• Molecular Weight :

  345.30

• References & Citations :

  [1]Robinson MJ, et al. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991;266 (22) :14585-14592.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Topo II

• CAS Number :

  [103978-08-1]