9S-HODE

• Description :

  9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO[1][2].

• Product Name Alternative :

  Alpha-dimorphecolic acid

• UNSPSC :

  12352211

• Hazard Statement :

  H225, H319

• Target :

  Apoptosis; Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/9s-hode.html

• Concentration :

  5.31 mM * 63.5 μL in Ethanol

• Purity :

  98.0

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O

• Molecular Formula :

  C18H32O3

• Molecular Weight :

  296.44

• Precautions :

  H225, H319

• References & Citations :

  [1]Liu S, et al. Linoleic acid derivatives target miR-361-3p/BTG2 to confer anticancer effects in acute myeloid leukemia. J Biochem Mol Toxicol. 2023 Nov;37 (11) :e23481.|[2]Spiteller P, et al. 9-Hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic acid (13-HODE) : excellent markers for lipid peroxidation[J]. Chemistry and Physics of Lipids, 1997, 89 (2) : 131-139.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [73543-67-6]