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9S-HODE

CAT: 0804-HY-113455Size: 100 μg (5.31 mM x 63.5 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-113455Size:100 μg (5.31 mM x 63.5 μL in Ethanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO[1][2].
CAS Number
73543-67-6
Product Name Alternative
Alpha-dimorphecolic acid
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Apoptosis; Endogenous Metabolite
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/9s-hode.html
Concentration
5.31 mM * 63.5 μL in Ethanol
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O
Molecular Formula
C18H32O3
Molecular Weight
296.44
Precautions
H225, H319
References & Citations
[1]Liu S, et al. Linoleic acid derivatives target miR-361-3p/BTG2 to confer anticancer effects in acute myeloid leukemia. J Biochem Mol Toxicol. 2023 Nov;37 (11) :e23481.|[2]Spiteller P, et al. 9-Hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic acid (13-HODE) : excellent markers for lipid peroxidation[J]. Chemistry and Physics of Lipids, 1997, 89 (2) : 131-139.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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