9S-HODE

• UNSPSC Description:

  9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO[1][2].

• Target Antigen:

  Apoptosis; Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/9s-hode.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O

• Molecular Weight:

  296.44

• References & Citations:

  [1]Liu S, et al. Linoleic acid derivatives target miR-361-3p/BTG2 to confer anticancer effects in acute myeloid leukemia. J Biochem Mol Toxicol. 2023 Nov;37(11):e23481.|[2]Spiteller P, et al. 9-Hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic acid (13-HODE): excellent markers for lipid peroxidation[J]. Chemistry and Physics of Lipids, 1997, 89(2): 131-139.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  73543-67-6