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9 (S) -HODE-13C18

CAT: 0804-HY-113455S1Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-113455S1Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
9 (S) -HODE-13C18 ((+) -α-Dimophecolic acid-13C18) is 13C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO[1][2].
Product Name Alternative
(+) -α-Dimophecolic acid-13C18
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/9-s-hode-13c18.html
Smiles
O[13C]([13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13C@@H](/[13CH]=[13CH]/[13CH]=[13CH]\[13CH2][13CH2][13CH2][13CH2][13CH3])O)=O
Molecular Formula
13C18H32O3
Molecular Weight
314.31
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Liu S, et al. Linoleic acid derivatives target miR-361-3p/BTG2 to confer anticancer effects in acute myeloid leukemia. J Biochem Mol Toxicol. 2023 Nov;37 (11) :e23481.|[3]Spiteller P, et al. 9-Hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic acid (13-HODE) : excellent markers for lipid peroxidation[J]. Chemistry and Physics of Lipids, 1997, 89 (2) : 131-139.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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