(±)9-HODE cholesteryl ester

• UNSPSC Description:

  (±)9-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL.2 Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 9-HODE cholesteryl ester.

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/racemic-9-hode-cholesteryl-ester.html

• Smiles:

  CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCCC(O)/C=C/C=C\CCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

• Molecular Weight:

  665.08

• References & Citations:

  [1]Belkner, et al. The oxygenation of cholesterol esters by the reticulocyte lipoxygenase. FEBS Lett. 279(1), 110-114 (1991).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  33783-76-5