(±) 9-HODE cholesteryl ester

• Description :

  (±) 9-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL.2 Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 9-HODE cholesteryl ester.

• UNSPSC :

  12352211

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/racemic-9-hode-cholesteryl-ester.html

• Smiles :

  CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCCC(O)/C=C/C=C\CCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

• Molecular Formula :

  C45H76O3

• Molecular Weight :

  665.08

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Belkner, et al. The oxygenation of cholesterol esters by the reticulocyte lipoxygenase. FEBS Lett. 279 (1), 110-114 (1991) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [33783-76-5]