AT-121

CAT: 0804-HY-112692Size: 100 μg (2.16 mM x 100 μL in Chloroform)Dry Ice: NoHazardous: No
CAT#:0804-HY-112692Size:100 μg (2.16 mM x 100 μL in Chloroform)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AT-121 is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects[1].
CAS Number
[2099681-31-7]
UNSPSC
12352005
Hazard Statement
H302-H310-H315-H319-H331-H351-H361-H372
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/at-121.html
Concentration
2.16 mM * 100 μL in Chloroform
Purity
99.73
Solubility
10 mM in DMSO
Smiles
O=S(N)(NCCN1CC2=C(C=CC=C2)C3(CCN([C@H]4CC[C@@H](C(C)C)CC4)CC3)C1=O)=O
Molecular Formula
C24H38N4O3S
Molecular Weight
462.65
Precautions
P260-P261-P262-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ding H, Kiguchi N, Yasuda D, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018;10 (456) :eaar3483. doi:10.1126/scitranslmed.aar3483
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR

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